Dry eye is painful! Sorry about that. Restasis worked for me - I have severe dry eye and epithelial dystrophy. (Opening my eyes in the morning used to be accompanied by searing pain as my corneas were adhered to the insides of my eyelids.) I won't kid ya, Restasis is very expensive however, per my eye doc, if you get the individual droppers you can reattach the snap off top and get two days out of one dropper. I then "skid stock" them in the second half of the year once I've reached my deductible and have a supply that lasts me at the beginning of the next year until I once again hit my deductible. Oh, after several years I found I could drop down to one dose a day instead of two also reducing the net cost. (But doc still prescribes as if I take twice a day so I can "skid stock") Fish oil (even before DS) did nothing nor did plugging tear ducts. Good luck.