Dr. Google and I probably didn't find anything you don't already know:
Pituitary tumors that secrete corticotropin can cause Cushing disease (
http://emedicine.medscape.com/article/126702-overview):
Corticotropin-secreting adenomas cause Cushing disease characterized by weight gain, primarily in the facial, nuchal, truncal, and girdle areas (ie, centripetal or "buffalo" obesity). Protein breakdown leads to thin, friable skin that bruises easily; this breakdown may form wide striae that are often purple. The protein breakdown often causes muscle weakness (proximal muscles more than distal muscles), wasting, and osteopenia with fragility fractures. Women often develop hirsutism. In children, growth is arrested.
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Cushing syndrome is best treated with surgical resection of the microadenoma, if possible. Medical alternatives, especially after surgical failure, include a new long-acting somatostatin agonist pasireotide, a glucocorticoid receptor antagonist mifepristone, or adrenal steroidogenesis inhibitors such as ketoconazole.
Surgery to remove microtumors in the pituitary are usually done through the nose:
http://pituitary.mgh.harvard.edu/TranssphenoidalSurgery.htm
After addressing and fixing this problem, which I hope will not be a terrible ordeal once they figure out what needs to be done, one must ask why another neuroendocrine tumor in the family - albeit a different type?
