What is your microbiome and why is it important?

JackieOnLine

Moderator
Staff member
I hope you find it interesting.

I recognize that my GI tract is very different from everyone else's here (mostly) but, still, we all need to know about this.

3 - 5 pounds (think of it) of bacteria living in your colon and having a tremendous influence on your immune systems and moods and appetite.

it's really mind-boggling.
 

JackieOnLine

Moderator
Staff member
our (sick) view of eating/food in this society sees fiber as something that is only good for the bulk needed to move our bowels.

when it is actually the ONLY source of nutrients for our microbiome.
 

Georgepds

Well-Known Member
Not completely sure, but I thought most of the microbiome was in the large intestine... so , those of us with VSG &DS should have similar response to fiber
 

JackieOnLine

Moderator
Staff member
yes, the microbiome is in the large intestines living off whatever it's host wasn't able to digest.
 

hilary1617

First time at the rodeo.
There's this too -- Fecal transplants might not just be for C-diff anymore, and while the study cited is small, it's promising: https://www.businessinsider.com/fecal-transplants-being-touted-new-treatment-for-skin-cancer-2021-2

Fecal transplants, made up of poop and microbes, are being touted as a promising new treatment for skin cancer patients
Joshua Zitser

Fecal transplants, which are made up of poop and microbes, could be used to tackle melanoma.

  • The procedure involves transplanting healthy poop into the gut of a skin cancer patient.
  • A study suggests that these transplants could help patients respond better to immunotherapy.
Fecal transplants are being touted as a promising new treatment for patients with a serious form of skin cancer, according to research seen by The Guardian.

The transplants, which are made up of poop and microbes, could be used to help those suffering due to melanoma.

The procedure would involve transplanting stool from a healthy donor into the gut of a melanoma patient, the paper said.

This, in turn, may help the patient respond better to immunotherapy, the research suggests.

Melanoma, the most serious type of skin cancer, frequently requires different types of immunotherapy for treatment.

There are signs from this study that suggest that the chances of successful immunotherapy treatment might be boosted by fecal transplants.

In the study, healthy stool was taken from seven people who had responded positively to the immunotherapy drug pembrolizumab. The stool was then transplanted into the guts of 15 melanoma patients.

After receiving the transplant, the patients were prescribed pembrolizumab every three weeks. They were then monitored over a period of a year, reported The Guardian.

The research showed that six of the patients responded positively to the drugs, with three of them seeing a large decrease or total eradication of the skin cancer.

Among all of the patients, there were promising signs of an increased survival time. The median survival time was boosted from seven months to 14 months, the paper said.

While the results offer hope for treating melanoma patients, the study was only conducted on a small number of patients.

The authors of the study told The Guardian that they hope to carry out the trials on a large group of melanoma patients and to test the impact of fecal transplants on other cancers.
 
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