SADI-S Data

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Posted by Elizabeth Gilchrist on Living with the Traditional Duodenal Switch

We have been waiting for long term SADI data. A 2021 journal article about the 5-year results in 1254 patients given RNY or SADI came from the Salt Lake City Bariatric Group, led by Dr Daniel Cottam. The common channel was 300 cm. About one-fifth of SADI patients at 5 years fail to maintain 50% of the weight they had lost at at 18 months. The long-term weight-loss failure rate (defined as failure to maintain 50% of weight loss at 18 months) was compared between RNY and SADI. Although the rate was significantly higher in the RYGB group [36%], the failure rate was 21.3% in SADI patients. (Surve, Obesity Surgery 2021).

There was no significant difference in weight outcomes between RNY and SADI at the end of the study. “In both groups, RNY and SADI-S, there was no statistically significant difference in weight loss between 5 and 6 years.”

SADI patients benefited from a lower complication rate than RNY. This is the link to the study.
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The same team has look at diabetes resolution with SADI in a 2020 report, which was 77% ( Surve, 2020). This is a lower rate of diabetes resolution than DS or RNY in the stats I could find.

Surve et al 2021 reported there was was no statistically significant difference between the RNY and SADI groups for nutritional data such as vitamins D, B1, and B12; insulin; fasting blood glucose; A1C; serum albumin; serum total protein; and triglycerides. This is their supplement regimen “For the RYGB patients, we recommended a multivitamin, calcium citrate (1500 mg/day), iron (if needed [65 mg/day]), vitamin B12 (1000 mcg/week), vitamin D (5000 IU per day), and probiotics (daily). For the SADI-S group, we recommended ADEK multivitamin, calcium citrate (1800–2400 mg/day), iron (65 mg/day), vitamin, and probiotics (daily).”

I am sure there is a lot to say about this study, but I can only hope that surgeons fully discuss the results with future patients.
 
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